Πλοήγηση ανά Συγγραφέα "Triantafyllou, A."
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Cobalt induces hypoxia-inducible factor-1 alpha (HIF-1 alpha) in HeLa cells by an iron-independent, but ROS-, PI-3K- and MAPK-dependent mechanism
Triantafyllou, A.; Liakos, P.; Tsakalof, A.; Georgatsou, E.; Simos, G.; Bonanou, S. (2006)The iron-chelator desferrioxamine (DFO) and the transition metal cobalt induce hypoxia-inducible factor-1 alpha (HIF-1 alpha) in normoxia. DFO stabilizes HIF-1 alpha from proteolysis by inhibiting the activity of iron-dependent ... -
Derivation of strain gradient length via homogenization of heterogeneous elastic materials
Triantafyllou, A.; Giannakopoulos, A. E. (2013)We present explicit upper bound estimates of the microstructural length used in simple gradient elasticity. Our model is a two dimensional composite made of circular hard inclusions randomly dispersed in a soft matrix. ... -
Differential regulation of hypoxia inducible factor 1 alpha (HIF-1 alpha) expression and HeLa cell survival and proliferation by hypoxia, desferrioxamine, cobalt and quercetin: the role of iron
Triantafyllou, A.; Liakos, P.; Tsakalof, A.; Georgatsou, E.; Simos, G.; Bonanou, S. (2005) -
The flavonoid quercetin induces hypoxia-inducible factor-1 alpha (HIF-1 alpha) and inhibits cell proliferation by depleting intracellular iron
Triantafyllou, A.; Liakos, P.; Tsakalof, A.; Chachami, G.; Paraskeva, E.; Molyvdas, P. A.; Georgatsou, E.; Simos, G.; Bonanou, S. (2007)Quercetin, a flavonoid with anti- oxidant, metal chelating, kinase modulating and anti- proliferative properties, can induce hypoxia- inducible factor-1 alpha (HIF-1 alpha) in normoxia, but its mechanism of action has not ... -
Flavonoids induce HIF-1 alpha but impair its nuclear accumulation and activity
Triantafyllou, A.; Mylonis, L.; Simos, G.; Bonanou, S.; Tsakalof, A. (2008)Hypoxia-inducible factor-1 alpha (HIF-1 alpha) is the regulatory subunit of the transcription factor HIF-1, which is highly involved in the pathology of diseases associated with tissue hypoxia. In this study we investigated ... -
Gradient Elastodamage Model for Quasi-Brittle Materials with an Evolving Internal Length
Triantafyllou, A.; Perdikaris, P. C.; Giannakopoulos, A. E. (2015)The article presents a new approach based on a strain gradient damage constitutive law for modeling quasi-brittle materials such as concrete. The authors use a weak type nonlocal formulation of the problem, relying on ... -
The impact of frequently encountered cardiovascular risk factors on sexual dysfunction in rheumatic disorders
Anyfanti, P.; Pyrpasopoulou, A.; Triantafyllou, A.; Doumas, M.; Gavriilaki, E.; Triantafyllou, G.; Gkaliagkousi, E.; Chatzimichailidou, S.; Petidis, K.; Avagianou, P. A.; Zamboulis, C.; Aslanidis, S.; Douma, S. (2013)Traditional cardiovascular risk factors have been acknowledged as major contributors to sexual dysfunction in the general population. The purpose of this study was to explore their impact on sexual function in rheumatologic ... -
Spherical indentation of incompressible rubber-like materials
Giannakopoulos, A. E.; Triantafyllou, A. (2007)In recent years, indentation tests have been proven very useful in probing mechanical properties of small volumes of materials. However, a class of materials that very little has been done in this direction is rubber-like ... -
Structural analysis using a dipolar elastic Timoshenko beam
Triantafyllou, A.; Giannakopoulos, A. E. (2013)In recent years, several non-local beam theories have emerged in trying to model stiffness and strength phenomena observed in micro-beams used in micro-mechanical systems (MEMS) and sensors. Of particular importance are ...